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10.1016/j.cmet.2014.09.018 46 ForetzM.GuigasB.ViolletB
The winning approach isnt picking a drugits designing a system: start with orals where appropriate, reserve high-cost injectables for highest-risk members, and plan for step-up (and step-down) pathways as newer therapies emerge
Your personal response determines whether dose escalation continues or whether you maintain benefits at a lower level
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