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14,15 Another meta-analysis of 93 clinical trials showed that GLP-1 RAs increased the risk of early-stage DR compared with placebo, with this effect being driven by albiglutide in particular
Maximum dosage strength of 15 mg is rarely used owing to its potency and severity of side effects such doses cause
In clinical trials, patients using semaglutide experienced significant weight reduction compared to those on a placebo
The Intensifying GLP-1 Race While Novo Nordisk recently secured FDA approval for an oral version of semaglutide becoming the first to market an oral GLP-1RA for obesity Eli Lilly continues to lead in injectable sales with: Zepbound (obesity) Mounjaro (type 2 diabetes) Lilly is also awaiting an FDA decision on its oral candidate, orforglipron
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