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Fatigue and Cognitive Impairment First-generation antihistamines (like diphenhydramine/Benadryl and hydroxyzine) are notorious for causing drowsiness because they cross the blood-brain barrier and block H1 receptors in the central nervous system
GSH in Cancer Dual Roles in Carcinogenesis and Drug Resistance (PubMed, 2019) Elevated Tumour GSH as a Driver of Chemotherapy Resistance A comprehensive review published on PubMed examined GSHs dual roles in cancer biology chemopreventive in normal cells through carcinogen detoxification by GST, and pathogenic in tumour cells where elevated GSH levels are associated with tumour progression and increased resistance to chemotherapeutic drugs and radiotherapy
All statistical analyses were conducted using R software (version 4.2.3, R Foundation for Statistical Computing, Vienna, Austria)
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