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The primary CLL lymphocytes were incubated for 24 hours with CB-839 and ibrutinib

In addition, unlike studies in human volunteers, which have historically comprised the majority of fMRI research [62] the specific mechanisms that alter functional connectivity in GLP-1R KO mice versus WT mice can be investigated with the full toolset available to rodent neuroscience

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It is part of a complex antioxidant system that works synergistically to retain redox balance