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GHK-Cu and copper uglies Albeit rare, some people may experience a side effect from using GHK-Cu or other copper peptides known as copper uglies. Though there arent any studies on this phenomenon, some users have anecdotal reports of copper peptide skin care products leading to what looks like accelerated skin aging instead of antiaging

Park S, Park SK (2022) Anti-oxidant and anti-aging effects of phlorizin are mediated by DAF-16-induced stress response and autophagy in Caenorhabditis elegans

This is most probably because they burn more body fat while at the same time preserving muscle glycogen

those datasets are cited generically here because independent replication is not available