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This well-defined coordination structure not only effectively stabilizes ruthenium single atoms and atomic clusters but also mitigates their undesirable aggregation and detachment from the substrate[51]

Most shedding occurs due to rapid weight loss, nutritional deficiencies, and metabolic stress that affect the hair growth cycle

Among these, transdermal systems, including patches, are being explored for their ability to provide sustained drug release while bypassing first-pass metabolism

The PEG moiety also reduces immunogenicity and improves aqueous solubility, which are practical advantages in cell culture systems