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But patients who jump doses, who go from 2.5mg straight to 7.5mg, or who escalate every two weeks instead of every four, report significantly worse GI symptoms that sometimes require medical intervention
According to the SURPASS-5 clinical trial, after 40 weeks on varying doses of tirzepatide, participants experienced an average reduction in A1C of 2% with the 5 mg dose, 2.4% with the 10 mg dose, and 2.34% with the 15 mg dose
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