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In a head-to-head study (SURPASS-2), Mounjaro topped Ozempic (1 mg semaglutide), showing it was more effective in helping patients keep their blood sugar levels in check and lose weight
Melanocortins (MCs) are multifunctional peptide hormones that regulate a diversity of physiological functions
They can counteract weight gain from steroid medications
PCA analysis based on the metabolomic state revealed distinct clustering of the two cohorts, suggesting a distinct metabolic BM microenvironment in LTR compared to STR (Fig
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