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Cagrilintide is in active clinical development
Oncogene 25:163948, PMID: 16550164 Coles BF, Morel F, Rauch C, Huber WW, Yang M, Teitel CH, Green B, Lang NP, Kadlubar FF (2001) Effect of polymorphism in the human glutathione S -transferase A1 promoter on hepatic GSTA1 and GSTA2 expression
28 In typical organisms, the generation and clearance of ROS are maintained in a balanced state (redox homeostasis)
Oxidative stress is also amplified by the loss of anti-oxidant capabilities and increased production of inflammatory cytokines
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