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I.ChowdhuryJ
The high neutrophil to lymphocyte ratio in critically ill patients, the intense neutrophil infiltration in pulmonary capillaries and into pulmonary alveoli, and the increased levels of circulating neutrophil extracellular traps (NETs) clearly show neutrophil involvement/activation favoring intense ROS production and oxidative damage caused by lipid peroxidation, and protein and DNA oxidation (Komaravelli and Casola, 2014
Iron and the liver
Based on the THCA prognostic risk model, we screened the key molecule Ribonucleotide reductase M2 ( RRM2 ) subunit, which has a potential pro-cancer role, to explore the functional role of RRM2 and its molecular mechanism in PTC, and to investigate the effects of RRM2 on the proliferation, apoptosis, migration invasion, cell cycle, and tumorigenicity of PTC cells in vivo
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