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Access this article Similar content being viewed by others Data Availability The datasets used and/or analyzed during the current study are available from the corresponding author upon reasonable request
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Treatment with ATR-127 in diet-induced mice with obesity showed that ATR-127 effectively improved glucose homeostasis, reduced body weight and fat mass, enhanced skeletal muscle glucose uptake, increased brown adipose tissue thermogenesis, and improved hepatic steatosis 55
GSH supplements would seem to be the most efficient way to increase cellular levels of GSH because if significant amounts of GSH are absorbed intact and are biologically active and also if the digestion process breaks down additional amounts of the supplemental GSH into its precursorswhich would then be also absorbed and available for recombination into GSHthe inter- and intracellular GSH transport mechanisms would be shifted in favor of increased cellular GSH
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