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While in vitro equilibrations between redox couples such as roGFP2 and GSH/GSSG require minutes or even hours to reach a thermodynamic endpoint (G = 0), enzyme-catalyzed thiol-disulfide exchange reactions usually occur very rapidly and either maintain or reach a steady state (G 0) 7,31,32,60,63,67,78,79
Tirzepatide is a newer medication and is still being assessed for its long-term effects and potential additional benefits, such as cardiovascular outcomes
The biggest issues are not whether you are hypothyroid, but whether you have rare thyroid cancer risks, whether your thyroid hormone dose remains appropriate, and whether your thyroid labs are monitored as weight changes