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Hyperglycemia and lipotoxicity drive sustained ROS production through NADPH oxidase (NOX4), mitochondrial respiratory chain complexes I and III, and xanthine oxidase, while concurrently depleting antioxidant defenses such as glutathione (GSH), superoxide dismutase (SOD2), and catalase
MT-2 efficacy in treating sexual dysfunction in men and women
This condition commonly follows major physiological stressors, including rapid weight loss, caloric restriction, and nutritional deficiencies
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