Additionally, these medications enhance glucose-dependent insulin secretion from pancreatic beta cells whilst suppressing inappropriate glucagon release, thereby improving glycaemic control in individuals with type 2 diabetes
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Funding This research was supported by the Arkansas Biosciences Institute (Little Rock, AR, USA), The Jonty Foundation (St Paul, MN), The Autism Research Institute (San Diego, CA), the Gupta Family Foundation (Atherton, CA), The Jane Bostford Johnson Foundation (New York, NY) and the Jager Family Foundation (Chicago, IL)
While Novo Nordisk began clinical testing of liraglutide for obesity, Knudsens team embarked on a series of studies using radioactivity to trace the drugs path through the bodies of mice