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464 TeraoJ.PiskulaM.YaoQ
GLP-1s are the most sought-after medication of this generation, and for good reason: Not only do they effectively manage diabetes, but they also have powerful weight-loss benefits for people with obesity
Thus, blockade of hepatic portal GLP-1R signaling causes glucose intolerance in rats, suggesting that GLP-1Rs located on nerve terminals in the hepatic portal vein contribute to the incretin action of GLP-1 (Vahl et al., 2007)
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