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As these drugs become more effective and accessible, clinicians need better guidelines around who qualifies for which medication, Yerevanian says

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Specifically, uncontrolled elevated intracellular lactate concentrations disrupt the NADH/NAD+ ratio, thereby impairing the activity of key glycolytic enzymes, particularly GAPDH due to NAD+ depletion (50,57)

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Loan A, Leung JW, Cook DP, Ko C, Vanderhyden BC, Wang J, Chan HM (2023) Prenatal low-dose methylmercury exposure causes premature neuronal differentiation and autism-like behaviors in a rodent model

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