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The STEP-HFpEF trial, which focused on patients with heart failure and preserved ejection fraction who also had obesity, found that semaglutide (2.4 mg) resulted in greater reductions in symptoms, enhanced physical function, improved exercise capacity, and greater weight loss compared with placebo [75]

This includes genes governing collagen synthesis, anti-inflammatory cytokines, antioxidant defense, and tissue remodeling pathways

Emerging technologies such as liquid biopsy, next-generation sequencing (NGS), and single-cell and spatial sequencing have enabled dynamic and comprehensive monitoring of tumor evolution and heterogeneity

Fingolimod and diabetic retinopathy: A drug repurposing study