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Metabolomic adaptations and correlates of survival to immune checkpoint blockade

[14] [15] The choice between agents should be individualised based on factors including: Efficacy requirements (glycaemic control and weight loss goals) Tolerability profile (gastrointestinal adverse effects vary between agents) Patient preference regarding injection frequency and device Cost and formulary availability (as per local NHS commissioning) Comorbidities (cardiovascular outcome evidence and licensed indications vary by product

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