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Alteration in gut mycobiota of patients with polycystic ovary syndrome
[7] Phospholipase C (PLC) may cleave phosphatidylinositol 4,5-bisphosphate (PIP2) into secondary messengers, IP3 and DAG (diacylglycerol)
By sequestering miR-889-3p, circUBE2D2 indirectly upregulates LDHA, increasing lactate production and enhancing sorafenib resistance in HCC cells [159]
As many naevomelanocytes in cutaneous naevi show activating mutations in the BRAF or in the NRAS intracellular signalling pathways which mediate cell proliferation and differentia-tion [11, 34, 42], naevi are considered by many to be benign naevomelanocytic neoplasias
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