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The medication also appears to have beneficial effects on the gut, including possible effects on the gut microbiome and intestinal glucose handling, though these mechanisms are still being fully elucidated
NICE recommends GLP-1 receptor agonists for people with a BMI 35 kg/m (or lower in certain ethnic groups), or when obesity-related complications are present, or when insulin would have significant occupational implications
It is supplied as a discreet, once- or twice-monthly self-injection for at-home use
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