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Premenopausal women with functioning ovaries typically have enough estrogen production to compensate for the loss from adipose tissue, though exceptions exist, especially with very rapid or very significant weight loss
In contrast, when utilising 30% U- 13 CR 6 -labelled arginine as the sole carbon source, there were only a few differences between the metabolic labelling in gdh3 / gdh3 and wild-type cells that included two TCA cycle intermediates (fumarate and cis -aconitate) and all three aromatic amino acids (phenylalanine, tryptophan, and tyrosine)
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