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The STEP UP trial, a Phase 3b study published in The Lancet Diabetes & Endocrinology in 2025, evaluated a 7.2 mg weekly injection dose in over 1,400 adults with obesity (BMI of 30 or higher) and without diabetes
Daily lessons to work on your habits
Semaglutides single-action mechanism solely activates the GLP-1 receptor to regulate insulin and appetite
It works by increasing neurotransmitter activity in brain regions responsible for attention and cognitive control, particularly the prefrontal cortex
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