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17,123 The phenotype of the disease represents the observable characteristics of the disease or patient (such as obstructive sleep apnea in the elderly, men, or Black patients), whereas the endotype refers to the underlying biological mechanisms which drive disease (such as fat distribution, hyporesponsive muscles of the airway, or abnormal craniofacial structures)
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There was no significant increase in gastrointestinal side effects in this small group of people who were already treated with and therefore known to be tolerant of normal-release metformin
doi: 10.1097/00001721-199910000-00006 350 HannanKLBergDEBaumzweigerWHarrisonHHBergLHRamirezRet al
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