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To alleviate constipation, healthcare providers often recommend lifestyle modifications, including increasing dietary fiber intake, staying well-hydrated, and engaging in regular physical activity

Ozempic (GLP-1 receptor agonist) and Phentermine (the classic stimulant) are commonly used weight loss medications

Simultaneously, some cells undergo cell cycle arrest and become senescent owing to the inhibition of cyclin-dependent kinases mediated by p21 activation through the DDR pathway 11

The hypothesized increase in calcium ion concentration within the cells, along with the potential activation of PKC, might lead to the exocytosis of vesicles that contain growth hormones