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Except for a few weight-related conditions (e.g., arthritis, sleep apnea), its controversial whether excess weight is actually a health hazard

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This means that the dosing question is not just "how much" but "for how long." A researcher who reaches their goal weight at month 8 needs to consider whether to continue at a maintenance dose, reduce to a lower maintenance level, or taper off with the understanding that some regain is likely