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2 Approximately 60% of people diagnosed with obesity or overweight have at least one comorbidity
In others particularly at higher doses or during dose escalation the net effect may be altered intestinal motility and transit patterns that result in looser stools or diarrhoea
These criteria include reduced mobility, increased arousal threshold, rapid reversibility, place preference/posture, and homeostatic regulation (Campbell and Tobler 1984
Emerging evidence suggests that lactate exerts metabolic effects beyond its conventional role within these immune lineages, and also plays a multifaceted regulatory role
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