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CagriSema (cag + sema) is the closest analog with human trial data
This stepwise ubiquitination mechanism, involving distinct E2 enzymes for building ubiquitin chain, is reminiscent of other CRL4 complexes but highlights the unique modularity of the CRL4 DET1-COP1 system
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The JIATF-CC provided drone mapping and targeting support without displacing Mexican command authority, a balance that is harder to strike than it sounds given the domestic political pressures on both sides of the border
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