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Osteoarthr Cartil 20: 6467 Chen X, Xie C, Sun L, Ding J, Cai H (2015) Longitudinal metabolomics profiling of Parkinson's diseaserelated synuclein A53T transgenic mice

Figure 1 SAMe serves mainly as a methyl donor in the cell and transfers its methyl group to substrates such as nucleic acids, proteins, lipids, and secondary metabolites with the formation of S-adenosylhomocysteine (SAH, which is also abbreviated as AdoHcy), via transmethylation (3, 4)

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Glutathione is typically used multiple times per week during an initial support phase, followed by a maintenance schedule