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Abstract Myogenic stem cell activator HGF (hepatocyte growth factor) undergoes nitration of tyrosine residues (Y198, Y250) predominantly on fast-twitch fibers to lose its binding affinity to the signaling receptor c-met, in response to peroxynitrite (ONOO - ) generation during aging
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Their study, through FTIR spectroscopy, establishes firm bonds (such as C=O at 1688 cm) to ensure stable encapsulation
To maintain results, some patients may require ongoing treatment with maintenance injections at regular intervals
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