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By inhibiting calcium influx, exendin-4 reduces the calcium overload, which leads to apoptosis and excitation-induced neurotoxicity in RGCs, promoting RGC survival and function in DR (Wang et al., 2023)

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A 2020 systematic review and meta-analysis found a multi-strain probiotic reduced intestinal transit by 13.75 hours, increased stool frequency, improved stool consistency, and decreased bloating 36