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The authors acknowledged certain study limitations and emphasized that these findings underscore the need for patient-centered nutritional guidance, potentially involving Registered Dietitian Nutritionists, to optimize health outcomes and address identified dietary education gaps
Some individuals may increase more slowly, pause dose increases, or remain at a lower effective dose
Some studies point to monthly reductions averaging about 10% but potentially rising to 25%-45% as dosing levels increase
All reagents were dissolved and diluted in 50 mM KPi, pH 8.0
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