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The dose is very low and safe to be given with HRT

Moreover, folate is critical for pregnant women to reduce the risk of birth defects.* CARDIOVASCULAR SYSTEM HEALTH* CAN REDUCE RISK OF BIRTH DEFECTS*^ ^Women who consume healthful diets with adequate folate throughout their childbearing years may reduce their risk of having a child with a birth defect of the brain or spinal cord

The fractions for monomeric complex were collected and concentrated to 15-20 mg/mL for electron microscopy examination