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Such an alteration may strengthen G protein coupling by introducing several newly formed polar interactions such as two salt bridges (R176 2.46b and E408 8.49b , E423 8.64b and R46 in G)
Gong X, Ma M, Fan X, Li M, Liu Q, Liu X, Xu G: Down-regulation of IGF-1/IGF-1R in hippocampus of rats with vascular dementia
It can wake up miniaturized but viable follicles
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