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As a result Novo Nordisk and the National Institutes of Health funded a randomised, double-blind, controlled trial to look at the issue
The peptide has demonstrated efficacy in normalizing pathological blood pressure states, reversing hypertension induced by NOS inhibitors and attenuating hypotension induced by excessive NO substrate administration, indicating adaptive vascular regulation
Its important not to self-administer without medical guidance
The same reward biology helps explain addiction, binge eating, obesity, and GLP-1 treatment of SUDs
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