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In the first trial, liraglutide lowered weight by 12 pounds and improved glucose tolerance relative to placebo over 4 months in 103 patients with schizophrenia spectrum disorders (Larsen JR et al, JAMA Psych 2017;74(1):719728)
Possible rare but serious side effects include: Inflammation of the pancreas (pancreatitis) Complications of the eye disease diabetic retinopathy in people with type 2 diabetes Gallbladder disease Low blood sugar ( hypoglycemia ) Lung aspiration (inhaling food or fluids into the lungs) during general anesthesia or deep sedation for a medical procedure Severe allergic reactions like anaphylaxis Kidney injury Gallstones or inflammation of the gallbladder Ozempic has a black box warning about an increased risk for thyroid C-cell tumors
Contraindications according to UK SmPCs include hypersensitivity to the active substance or any excipients
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