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Mild cramping, early fullness or post-meal discomfort is expected early on in treatment or after dose increases and tends to improve with time
Thyroid function tests (TSH, free T4) should be checked at baseline, 6-8 weeks after achieving maintenance dose of the weight loss medication, and every 3-6 months during active weight loss to ensure appropriate thyroid hormone replacement
But having a backup plan and documenting all communications is wise
Lancet (2021) 398(10296):26276
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