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meningitidis MC58, gdhA expression was particularly increased in response to glucose in vitro , a condition that decreased the expression of TCA cycle genes ( gdhA transcription from gdhA P2 is significantly higher in vitro in meningococcal strains belonging to hypervirulent lines compared to those belonging to carrier lines expressing low levels of GhdR (Pagliarulo et al., 2004) as will be discussed below

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Corticosteroid interactions appear potentially favorable, with BPC-157 counteracting corticosteroid-induced healing impairment in some studies