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The FDA Adverse Event Reporting System (FAERS) contains reports of various gastrointestinal complications, though these reports have significant limitationsincluding underreporting, lack of denominator data, and inability to establish causality
The structural basis for this stability is not fully elucidated but may relate to its high proline content (3 consecutive Pro residues) which confers rigidity and protease resistance
Gut 37 , 766776 (1995)
86, 989, 1038, 1041 Bosy-Westphal, A
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