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In clinical practice, this conflict manifests as a time-benefit trade-off: Is the reproductive delay necessitated by a 36 months treatment phase and a subsequent 12 months washout period justified by the potential improvements in oocyte quality and endometrial receptivity
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For any synthetic AT developed, it is important to know which biomolecule the agent is designed to protect, by which mechanism (scavenging RS, preventing RS formation, increasing endogenous defense mechanisms, and/or supporting oxidative damage repair), whether it can generate RS, and if there are any adverse effects associated with RS suppression
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The drug manufacturer has filed multiple lawsuits to try to stop medical spas, weight loss clinics and compounding pharmacies from unlawfully selling the compounded drugs
Hyperphosphorylation of the tau protein can be mediated by activation of the p38MAPK/p53 signaling pathway (Sun et al., 2017)
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