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Peptides with hydrophobic motifs interact well with the lipid components of cell membranes, aiding their ability to penetrate cells 56
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Mutations in the gene encoding OCTN2, SLC22A5 , can impair fatty acid metabolism and lead to systemic primary carnitine deficiency (SPCD, OMIM 212140) 8 , an autosomal recessive disorder whose clinical manifestations include cardiomyopathy, hypoglycemia, chronic muscle weakness and liver dysfunction 9
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