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Moreover, GLP-1R cascade also has interactions to regulatory proteins involved in the insulin receptor cascades such as the insulin receptor substrates (IRS) and the PI3K involved in the positive regulation for survival, metabolism and proliferation of beta pancreatic cells as well as apical glucose transport in peripheral tissues
HO-1 is renowned for its positive impacts including anti-apoptotic, antioxidant, anti-nitrosative, as well as anti-inflammatory effects against iNOS among three isoforms
doi:10.1002/nbm.2772, PMID: 22281935 Puri BK, Agour M, Gunatilake KD, Fernando KA, Gurusinghe AI, Treasaden IH (2009) An in vivo proton neurospectroscopy study of cerebral oxidative stress in myalgic encephalomyelitis (chronic fatigue syndrome)
Nature 514 , 181186 (2014)
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