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Nutritional interventions leading to 5% weight loss are estimated to decrease LDL-C and non-HDL by 5%
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Some discontinue the sulfonylurea entirely once semaglutide reaches a therapeutic dose, since both target post-meal glucose and the GLP-1 mechanism is more physiologic
Leggio and his colleagues noted that, compared with other GLP-1 receptor agonists, semaglutide is more potent, has a higher affinity for its receptor, and is longer acting
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