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Sermorelin stimulates pituitary GH release, deepening slowwave (NREM) sleep but may modestly suppress REM, whereas Ipamorelin produces a more balanced increase in both deep and REM phases with fewer cortisol spikes

Dermatologica Sinica 2023, [Epub ahead of print]:[cited 2023 Mar 2021] Available from: Guyatt GH, Oxman AD, Kunz R, Woodcock J, Brozek J, Helfand M, Alonso-Coello P, Falck-Ytter Y, Jaeschke R, Vist G, et al

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