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Deficiency is particularly common in elderly people, because the ability to absorb vitamin B12 can decrease with age ( Other people at risk of deficiency include those who have had intestinal surgery, including weight loss surgery

Here, we present an integrated multi-omics and functional characterization of metabolic transitions during early differentiation of human induced pluripotent stem cells (iPSCs) into excitatory cortical neurons using doxycycline-inducible overexpression of neurogenin-2 (NGN2)

Free radicals can be caused by environmental factors such as pollution, UV radiation, and cigarette smoke, as well as internal factors such as inflammation and metabolism

Much of the safety data comes from animal studies, where researchers report on tolerance and effects in those models