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Addressing the mechanism of the H 2 O 2 -induced macrophage death, immunoblotting for cleaved caspase-3, measurement of released IL-1 and IL-18, and use of nercostatin-1 did not support caspase-3-dependent apoptosis, inflammasome activation or necroptosis as the underlying cause of the cytotoxicity, respectively
Preclinical findings should not be converted into broad claims
This process is gradual and systemic, leading to a natural, even-toned brightness rather than a harsh, unnatural lightning effect
Spraying solvent directly onto peptide powder damages the compound
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