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[4] Niacinamide (vitamin B) forms the coenzymes NAD and NADP, which are involved in hundreds of oxidation-reduction reactions in cells
This process is vital for normal metabolic function, muscle activity, and endurance
Pathological causes of elevated B12 warrant careful consideration: Haematological disorders : Myeloproliferative neoplasms (polycythaemia vera, chronic myeloid leukaemia), acute leukaemia, and lymphoproliferative disorders can increase B12-binding proteins (transcobalamin and haptocorrin), elevating total serum B12 [3] Liver disease : Hepatocellular damage releases stored B12 into circulation
The condition is accompanied by a decrease in the amount of protein in muscle tissue
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