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Rapid weight loss without adequate dietary fat leads to bile stasis, sludge formation, and gallstones requiring surgical intervention
PMID: 41139215 Nat Commun The TEX44-CPT1B axis regulates mitochondrial sheath assembly and fatty acid oxidation in sperm
Information based on Ro.co's January 5, 2026 announcement, Novo Nordisk public statements, and FDA regulatory information available at time of publication
A reader who wants to think clearly about it should hold two facts together without collapsing them: the acute, receptor-level case that cagrilintide slows the stomach is strong, and the chronic, whole-organism case that it keeps doing so is unproven
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