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contrast-enhanced CT scanning if diagnosis uncertain or complications suspected Management principles align with British Society of Gastroenterology guidance for acute pancreatitis and typically include: Hospital admission for most cases, with high-dependency or intensive care for severe presentations based on severity scoring Intravenous fluid resuscitation to maintain organ perfusion Analgesia (often requiring opioid medications for adequate pain control) Early oral or enteral nutrition when clinically safe and feasible, rather than prolonged fasting Treatment of underlying causes (e.g., endoscopic retrograde cholangiopancreatography for biliary obstruction) Tirzepatide should not be restarted following confirmed pancreatitis, as specified in the MHRA product information, and alternative diabetes or weight management therapies should be considered

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