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However, the mechanisms involved, whether therapeutic or side effects, are not fully understood
Landree LE, Hanlon AL, Strong DW, Rumbaugh G, Miller IM, Thupari JN, Connolly EC, Huganir RL, Richardson C, Witters LA, Kuhajda FP, Ronnett GV: C75, a fatty acid synthase inhibitor, modulates AMP-activated protein kinase to alter neuronal energy metabolism
Since amitraz is considered to be an agonist in the octopaminergic system of arthropods [7], this mimicry could have resulted in its non-recognition as a foreign or xenobiotic compound and, therefore, not a metabolite of the GSTs
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