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Pernicious anaemia is caused by a deficiency in vitamin B12, due to atrophic gastritis, an autoimmune condition (immune system destroys self), in this case the parietal cells of the stomach that produce intrinsic factor, a glycoprotein that binds to vitamin B12 in the stomach and is essential for normal absorption of vitamin B12 in the small intestine into the blood
The overall orientation shifted from CuA towards the L4 region
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4.13 Manganese Manganese homeostasis is mainly achieved through hepatobiliary excretion
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